A Chinese man became the first recipient of pig lungs.
Genetically modified pig organs It has been transplanted He is 39, according to an August 26 report by Journal Nature.
The procedure was carried out by researchers last year at the first affiliated hospital of Guangdong Medical University in China.
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The man was brain dead after experiencing brain hemorrhage. The lungs survived 9 days.
The left lung came from a pig with six genome edits created by Chinese research firm Chengdu Clonorgan Biotechnology.
Pig organs have been successfully transplanted into humans in the past. Clinical trials Human pig liver and kidney transplants were lit in the US this year with greenery.
In this first trial, researchers and doctors aimed to determine how the lungs hold up against humans. Immune response And the possibility of “overheating rejection.”
In an article in the Nature Journal, researchers reported the success of this recent transplant. This notes that there are no signs of rejection or infection within the 216-hour surveillance period.
During the first 24 hours, the team observed swelling of the lungs and tissue damage during the procedure.
On days 3 and 6, the team noticed damage caused by antibodies attacking organs, which had decreased by day 9.
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The research was then concluded at the request of Patient’s family On the nineth day, the report states.
“This study demonstrates the feasibility of xenografting of the lungs from pigs to humans, but there remain substantial challenges associated with organ rejection and infection,” the researchers concluded.
“More preclinical research is needed before clinical translation of this procedure.”
Muhammad Mohiudin, a surgeon and researcher at the University of Maryland School of Medicine in Baltimore, who led the first pig-heart transplant to live 2022, naturally said that the lungs are “the most difficult organ to transplant” because they depend on being attacked by the immune system.
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Mohiuddin praised the researchers’ efforts, calling it the “first step” towards the use of lung xenografts, or organs from other species to humans.
Fox News Digital has requested the researchers for comment.
