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Home»Health»Oprah reveals struggle with 'shame' of weight-loss drugs and what happened when she quit
Health

Oprah reveals struggle with 'shame' of weight-loss drugs and what happened when she quit

u1news-staffBy u1news-staffJanuary 15, 2026No Comments5 Mins Read
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Long-time talk show host oprah winfrey revealed that he recently succeeded in losing weight as a result of continuing to take GLP-1 (glucagon-like peptide-1).

Winfrey, 71, started taking the GLP-1 drug in 2023, but decided to see if she could stop after six months. lose weight Without that, according to a recent interview in People magazine.

Despite following his diet and exercise routine, the media mogul said he gained 20 pounds back after quitting drugs.

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“It’s going to be a lifelong thing,” she said. “I’m on high blood pressure medication, and if I were to stop taking my high blood pressure medication, my blood pressure would go up. I’ve realized that the same thing is true with these medications now. I’ve proven it myself.” [that] i need it. “

Winfrey revealed that her “default weight” of 211 pounds is not healthy. high cholesterol.

in a recent interview CBS NewsWinfrey revealed that she is currently down to 155 pounds and aims to keep it off.

“A combination of medication, daily hiking, and strength training has given me the body I had when I ran a marathon,” she said. “I mean, I was in great shape at 40, but to be 71 and still feel like I’m in the best shape of my life feels better than when I was 40.”

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On this week’s new episode of “The Oprah Podcast,” Winfrey welcomes Dr. Ania Jastrebov, an endocrinologist and associate professor at Yale University School of Medicine, to talk about GLP-1 weight loss drugs and her own personal journey. The two also co-authored a new book, Enough.

Winfrey said she initially had doubts about how it would be used. weight loss drugs Because of the prejudice that surrounds them.

“One of the reasons I was initially reluctant to use them was because I was trying to lose weight after knee surgery. [is] “Because I also felt like it was cheating and I felt like it was an easy way out,” she said, “I have to prove this to myself the last time I can. And I don’t want people to say I took the easy way out.”

Oprah joins wave of celebs who have revealed dramatic weight loss in 2025

“I think this is one of the big problems that people who tolerate drug use experience among their friends, coworkers, family, and themselves.”

Winfrey, one of the most powerful figures in American media, said she had been “publicly humiliated.” her weight 25 years.

“Anytime a comedian wanted to make fun of it or make a joke about it, they could make a joke about it, and I accepted it because I thought I deserved it,” she said. “I accepted it. I was ashamed of it, but I accepted it because I thought, ‘Well, they’re right.’ Now it turns out they were very wrong. ”

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Winfrey pointed out that many overweight people experience the same “levels of obesity,” even those who don’t appear on TV every day. embarrassment and embarrassment“Because I can’t control my weight.

“That feels like the punishment you deserve,” Winfrey said.

“Quite the opposite,” Jastrebov replied. “And none of this is in our control. For some reason, we as a society think we have control over how much we weigh, and that’s actually not the case. Our brains are in control.”

For more health stories, click here

Winfrey likened this to: addict’s brainpoints out that obesity is now considered as much a disease as addiction.

“For the past few years, I’ve thought that people who are thin just have more willpower, can eat better, last longer, and just never eat potato chips,” she said.

“And I noticed it the first time I took it. GLP-1 It’s…oh, they don’t even think about it. They only eat when they are hungry and stop when they are full. ”

Jastrebov agreed that while obesity is “not an addiction,” “food sounds,” or the urge to eat, use the same pathways in the brain.

The discussion continued with guest Amy (last name withheld). Amy is a GLP-1 patient who lost 160 pounds in one year. She said from her own experience, public shaming continues. “There is no chance,” Jastrebov replied.

“It’s shameful to be obese. It’s shameful not to try to lose weight. And it’s shameful to lose weight,” the doctor said. “If you use drugs, it’s embarrassing, but if you don’t use drugs… there’s literally no chance of winning.”

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“The right thing to do is to stop shaming and blaming people… [when] you are taking care of your health. ”

GLP-1 drugs are thought to be associated with several side effects, primarily in the gastrointestinal system. These usually include nausea, vomiting, diarrhea, constipation, and abdominal discomfort. Less commonly reported effects include fatigue, dizziness, and injection site reactions.

People interested in taking GLP-1 should talk to their doctor about recommended doses and potential risk factors.

039shame039 drugs happened Oprah quit reveals struggle weightloss
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