Aging appears to occur linearly throughout human life span, from childhood to the “golden age,” but new research reveals specific turning points. Aging begins to accelerate Inside the body.
Chinese researchers discovered that tissues and organs began to age at a faster pace around the age of 50.
“Body Clock” can determine biological age and longevity, researchers say
The findings were based on the study Of 516 samples taken from 13 human tissues over 50 years.
This analysis revealed a surge from about 50 years ago, leading to blood vessels “remarkably susceptible to aging.”
To understand the aging of individual organs, the researchers also collected tissue samples from 76 Chinese organ donors between the ages of 14 and 68. Brain injury.
The samples covered seven systems including cardiovascular, digestive, immunity, endocrine, respiratory, external (skin) and musculoskeletal, and blood samples.
Researchers have found that between the ages of 45 and 55, many tissues undergo “substantial proteome remodeling” (a major protein change), especially the aorta (the main cardiac artery), making them susceptible to aging.
“Together, our findings lay the foundation for a system-level understanding of human aging through protein lenses,” the researchers summarized.
Research co-author Guanghui Liu, a researcher at the Beijing Institute for Stem Cells and Regenerative Medicine, discussed the findings in an interview with Fox News Digital.
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Aging involves “multiorgan decline,” but this study aims to determine whether organs age in a “single rhythm.”
According to experts, certain substances in the blood – called “senocine” – act as a kind of clock that tracks and speeds up aging.
Researchers say blood vessels are one of the first parts of showing signs of aging, as they release proteins that can affect how the whole body ages.
Rather than occurring in one organ at a time, the findings suggest that aging should be considered a whole-body process.
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Liu suggested that linking plasma profiles with human body tissues may allow for “non-invasive” age assessments based on blood samples.
This helps to enable early targeted interventions Accelerated organ aging Reduces the risk of illness, he said.
