For the first time in 30 years, researchers believe they have identified New Classes of Antibiotics.
A team from McMaster University in Ontario, Canada, and the University of Chicago at the University of Illinois (led by researcher Jerry Wright) collaborated in the discovery of lariosidin, which was found to be effective against drug-resistant bacteria.
The results were published this week in Nature magazine.
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According to a press release from McMaster, lariosidin is a lasso-peptide, a set of lasso-shaped amino acids that attack bacteria, prevent them from growing and prevent them from survival.
For the first time in 30 years, researchers believe they have identified a new class of antibiotics (not photographed). (istock)
generated by a Types of bacteria Called Paenibacillus, researchers retrieved it from local backyard soil samples and were grown in the lab for a year.
Paenibacillus has been found to produce new substances that attack antibiotic-resistant bacteria.
“Lariosidine does not affect many of the mechanisms it creates Causes of illness Bacteria that are resistant to available antibiotics,” the researchers told Fox News Digital.
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The molecule has a unique structure of “knotted lasso or pretzel.”
“Lariosidin binds to the ribosome, a molecular machine, and makes all cellular proteins. This is one of the most important processes in a cell,” the researchers said.
This finding is important in light of the growth of antibiotic resistance, which the World Health Organization describes as a global public health threat. (istock)
“It binds to a specific site in the ribosome that does not bind to any of the known antibiotics, stopping the ribosome from making proteins.”
Another important advantage of lariosidin is that it is not toxic to human cells, researchers noted.
This finding is important in light of the growth of antibiotic resistance described by the World Health Organization globally Public Health It poses a threat that kills more than 4.5 million people around the world every year.
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“The antibiotic resistance crisis we are facing now represents a major threat to how we practice medicine,” the researcher told Fox News Digital.
“Infection must be prevented and treated in order to continue surgery, hip replacement and hip replacement. Cancer ChemotherapyTreatment of premature babies, etc. – As a result, new antibiotics are required to do this for a long period of time. ”
“The antibiotic resistance crisis we are facing now represents a major threat to how medicine is practiced.”
Dr. Marc Siegel, a senior medical analyst and professor of clinical medicine at Nyu Langone Health and Fox News, praised the finding.
“artificial intelligence We promise to improve the goals of new drugs, including antibiotics. And during that time, research at McMaster in Canada discovered a new class of antibiotics,” he told Fox News Digital.
Dr. Mark Siegel reiterated that a new class of antibiotics had not appeared in decades. (ISTOCK/FOX NEWS)
“This new kind of antibiotic – lariosidin – works by interfering with protein synthesis, which means that many bacteria need to survive.”
Siegel reiterated that a new class of antibiotics had not appeared in decades.
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Dr. Stephen Vogel, Family Medicine Physician on a Virtual Health Platform with Primary Care, Therapy and Primary Care Weight control The option said the finding represents a “promising answer” to tackling infections caused by drug-resistant bacteria.
“This microorganism can kill bacteria in ways that cannot be evolved to avoid due to a protein production system called ribosomes, making it a huge variety of deadly durable and permanent choices. Bacterial infection“The North Carolina-based doctor told Fox News Digital.
“While garden soil may seem mundane, it is in fact a unique universe of microorganisms, fungi and bacteria that could lead to important innovations like the promises this discovery brings,” one expert said. (istock)
According to Vogel, if the microorganism is introduced to the market as an antibiotic, it means that millions of people die from bacterial infections each year.
“While garden soil may seem mundane, it is in fact a unique universe of microorganisms, fungi and bacteria that could lead to important innovations like the promises this discovery brings,” he added.
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Future McMaster researchers will investigate how to modify and produce newly discovered molecules for use Clinical settingsa process that requires considerable time and resources.
“The discovery is just the starting point for a long process of developing this molecule into a drug,” the researchers told Fox News Digital. (istock)
“The discovery is just the starting point for a long process of developing this molecule into a drug,” the researchers told Fox News Digital.
“The next thing we have to do is that lariosidine, which can cure animals, Various infections With humanity. ”
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Researchers added that science is sometimes “accidental.”
“Perhaps, lariosidin certainly has to shovel a lot of dirt before finding a gem. Therefore, funding a ‘smudge shovel’ is important to find new gems. ”
