Author: u1news-staff

summary: Researchers have identified a novel role for the PIEZO2 protein in mediating chronic pain hypersensitivity, suggesting a new target for pain relief. The study shows that mutations in PIEZO2 make pain receptors, or pain receptors, hypersensitive to mechanical stimuli, causing persistent pain. This discovery may lead to new analgesics that effectively combat chronic pain by targeting PIEZO2 channels.Key Facts:Chronic Pain Links: Mutations in the PIEZO2 protein cause hypersensitivity of pain receptors.Pain receptor sensitivity: The mutation causes pain receptors to react as painful to light touch.New drug targets: Targeting PIEZO2 channels may improve the treatment of chronic pain.sauce: HelmholtzA research…

Fraser Harrison/Getty Images San Diego Comic-Con The full schedule for the 2024 edition has begun to be announced, and this year it will take place from July 25th to 28th. The annual conference is officially held at the San Diego Convention Center, but in reality, hordes of comic, genre, film and TV fans, as well as cosplayers, hit the streets in search of the latest news. Last year’s Comic-Con was lackluster due to the Hollywood strike, but this year, Deadline reports, it’s expected to return to its usual hustle and bustle. Marvel Studios plans return to Hall H — in…

There was a sparkle of a Stanley Cup over Erik Johnson’s right shoulder: a framed photo of the defenseman who will hoist it with the Avalanche in 2022. In the eyes of many, the 2024-25 Flyers are still A team in the process of rebuilding, or at least not yet a true championship contender.. But Johnson, a calm, well-spoken veteran who has seen a lot in his 16 seasons, wants the Flyers to think differently: The 36-year-old isn’t just returning to Philadelphia to play one more season and reach the milestone of 1,000 NHL games. He cherishes another opportunity. “Maybe…

Commentary: Divided and demoralized party stumbles ahead of November (Kevin Dietsch/Getty Images) President Biden’s big press conference at the NATO summit this week was a victory for his opponent, former President Trump. Why? Because Biden’s performance did nothing to resolve the Democrats’ dilemma over his status as the 2024 presidential nominee. The press conference gave Biden’s internal critics ammunition to denounce his candidacy, including his misidentification of Kamala Harris as “Vice President Trump.” But Biden’s answers to questions about foreign policy were strong enough to reassure his allies in the party, at least for now. As a result, Biden is…

Food inflation is slowing, and companies that produce food are starting to feel the strain.Snack-food giants PepsiCo Inc. and Conagra Brands Inc. reported declines in sales and unit sales in their quarterly earnings reports on Thursday, noting that cost-conscious consumers are pushing back against prices. Government data mirrored the trend, with the Bureau of Labor Statistics reporting that food prices rose slightly last month.”Consumers have become very price sensitive,” said Bobby Gibbs, partner in the retail and consumer goods practice at marketing consulting firm Oliver Wyman. “Consumers are becoming more selective about promotional pricing, and retailers are offering more promotional…

Researchers at Morphisec have discovered a critical zero-click remote code execution (RCE) vulnerability (CVE-2024-38021) in Microsoft Outlook. What has been revealed so far CVE-2024-30103However, this vulnerability is particularly dangerous because it does not require authentication. This zero-click remote code execution (RCE) vulnerability poses a significant threat as it can be exploited without any user interaction, especially when receiving emails from trusted senders. CVE-2024-38021 could have serious consequences, including data breach, unauthorized access, and other malicious activity. Join our free webinar Countering Slow DDoS Attacksis a major threat today. CVE-2024-38021 Vulnerability Details CVE-2024-38021 poses significant risks, including potential data breach, unauthorized…

Boeing Starliner astronauts Sunita Williams and Barry “Batch” Wilmore told reporters Wednesday they were confident the spacecraft would return them safely to Earth. In the meantime, Williams said they were both enjoying their long stay aboard the International Space Station. Image: NASA TV The crew of Boeing Co.’s Starliner spacecraft said Wednesday they are confident the spacecraft will return them safely to Earth at the end of a long stay aboard the International Space Station, despite a helium leak from the spacecraft’s propulsion system and problems with its steering thrusters. Starliner, which launched on June 5th, was originally scheduled to…

Cases of the potentially deadly Powassan virus are on the rise in Maine, and doctors are concerned. BRUNSWICK, Maine — First fatal case Powassan virus The new coronavirus outbreak in Maine this year has raised concerns among health experts. In June, Maine Center for Disease Control and Prevention An 81-year-old Sanford man has reportedly died from a tick-borne disease that can cause encephalitis in humans. Two additional cases, both of which have since recovered, have been confirmed this year in Kennebec and Lincoln counties, and seven cases were confirmed last year, including one that killed a Topsham man. This worrying…

Shark divers share their craziest diving experiences As if diving was already an exhilarating experience, you shark Add that to the mix and you’ll definitely get your adrenaline pumping! These divers Question He revealed his craziest experience with a shark. 1. Diver headbutted by shark 2. Diver attacked by tiger shark 3. Bull shark attacks diver during night dive Four. Diver bitten by mako shark Five. Diver runs out of air and gets surrounded by sharks 6. Diver attacked while searching for seahorses 7. The divers felt uneasy in the murky waters where there were sharks. 8. The daughter nearly…

Could you please hand me that something? It’s over there, next to the something.Many of us experience “lesologica,” or the inability to find words, in our daily lives, and this usually becomes more pronounced as we get older. Not being able to find the right words could be a sign of changes in the brain consistent In the early stages (the “preclinical” stage) Alzheimer’s disease The disease is detected before more obvious symptoms appear. but, Recent Research A University of Toronto study suggests that a more accurate indicator of brain health in older adults is the speed at which they…