Two inexpensive combinations of daily supplements helped fight the most terrifying diseases brain tumor According to new research, no side effects have been reported. But researchers say this approach is still experimental.
Scientists at the Advanced Center for Cancer Treatment, Research and Education (ACTREC) in Mumbai, India, found that the combination of resveratrol and copper “dramatically weakened” glioblastoma in a small group of patients, challenging the long-held idea that cancer must be attacked rather than cured.
Scientists led by Dr. Indranil Mitra, researcher and professor at ACTREC, conducted the study on 20 glioblastoma patients who were already scheduled for treatment. neurosurgeryaccording to a study published in the journal BJC Reports in September.
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Researchers observed major biological changes within the body. treated tumorThis includes almost complete removal of DNA fragments that cause inflammation and a significant reduction in several markers of tumor aggressiveness.
According to a research press release, no side effects were reported, and tumor growth activity was reduced by approximately 33%, cancer biomarkers were reduced by 57%, immune checkpoint signals were reduced by 41%, and stem cell markers were reduced by 56%.
“These results suggest that it is simple, inexpensive, and non-toxic. nutritional supplement tablets It has the potential to cure glioblastoma,” Mitra said in a statement.
Ten of the patients received tablets containing resveratrol and copper four times a day for about 12 days before surgery, and the remaining 10 received no supplements and served as controls. During the surgery, doctors took tumor tissue from all participants so they could compare treated and untreated tumors.
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Samples were analyzed to measure tumor growth, inflammation, immune activation, cancer stem cell markers, and the presence of cell-free chromatin particles. DNA fragment It is released by dying cancer cells and can worsen tumor behavior.
“We observed an almost complete removal of cell-free chromatin particles from cancerous glioblastoma tissue. [the resveratrol and copper] “This finding was particularly important because cell-free chromatin particles are a major factor in tumor aggressiveness,” Mitra told Fox News Digital.
of two supplements According to the study, the copper pairs up to allow resveratrol to generate a burst of reactive molecules that break down DNA debris, which is known to inflame cancer cells.
Resveratrol, a polyphenol found in foods like red grapes and berries, has been shown to have antioxidant properties in early studies, but it reacts differently when combined with copper, helping to dissolve harmful DNA fragments.
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“For 2,500 years, since the time of the ancient Greeks, we have been trying to kill cancer cells without success,” Mitra said. “Maybe it’s time to look at it.” cancer treatment It works toward curing the tumor rather than eliminating it. ”
He added: “We believe we may be on the cusp of changing the way cancer is treated.”
The researchers noted several limitations to the study, including the inclusion of only 20 patients. Also, because they only looked at short-term changes in tumor tissue and tested the supplement for just 12 days, it’s still unclear whether its effects actually improve outcomes.
They also said there was no change in the appearance of the tumors and the interaction of the supplements with standard treatment is still unknown.
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Larger, longer, and carefully controlled trials are needed to determine whether this is the case. resveratrol and copper The researchers pointed out whether it is safe to use long-term and whether it really improves the course of glioblastoma.
“The public should understand that our study is just a first step and our findings are based on a relatively small number of patients and need to be replicated in a larger patient cohort,” Mitra said.
“You should not start self-medicating just because these items are easily available,” he added. “Unless you use the controlled formulations we designed for research, you may see minimal benefit.”
Although supplements are widely available, they can pose risks for cancer patients and should only be used under the following conditions: medical supervisionaccording to the American Cancer Society.
Studies have shown that dietary supplements have no proven anticancer effects, may interfere with diagnostic tests, and have an uncertain safety profile and potential for interactions.
Mitra and his team have been studying this area of research for more than a decade. In 2024, the Tata Memorial Center, which oversees ACTREC, issued a statement warning of the initial resveratrol copper findings.
“It should be noted that resveratrol and copper, including its tablet formulation, are not established replacements. cancer treatment “Surgery, radiation therapy, chemotherapy, hormonal therapy, targeted therapies, etc., have been conclusively proven to be beneficial and curative for a significant proportion of patients,” the statement reads.
Fox News Digital has reached out to outside experts for comment.
