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Home»Health»Drugs that reduce dementia risk — and others that increase it
Health

Drugs that reduce dementia risk — and others that increase it

u1news-staffBy u1news-staffFebruary 25, 2025No Comments5 Mins Read
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Some medications may have the unintended benefits of reducing the risk of dementia.

It was based on a recent study by the University of Cambridge and Exeter, and researchers evaluated some Existing drugs Check whether you can double-work as a dementia treatment.

According to a press release, the team reviewed data from 14 previous studies, including over 130 million patients and 1 million cases of dementia.

They determined that several classes of prescription drugs were shown to affect the risk of dementia.

The risk of dementia can be reduced by doing this for five minutes a day.

The findings were published in Alzheimer’s Disease and Dementia: Translation Research and Clinical Interventions.

Researchers determined that several classes of prescription drugs have been shown to affect the risk of dementia. (istock)

“We need new treatments urgently to prevent the progression of dementia,” said Dr. Ben Underwood, co-author of the Department of Psychiatry at Cambridge University, Cambridgeshire University and Peterborough NHS Foundation Trust. release.

“If you can find drugs that are already licensed for other conditions, you can get them For trial And, very importantly, it may be possible for patients to make them available to them.

Drugs that reduce and increase risk

The study found that antibiotics, antivirals, anticoagulants (blood thinners) and anticonvulsants (drugs used to prevent or treat seizures) were all associated with a reduced risk of dementia.

Four vaccines – In case of A, hepatitis A, typhoid fever, hepatitis A, typhoid fever combination, and diphtheria were also associated with reduced risk.

Older man taking pills

“If we can find drugs that are already licensed for other conditions, we may be able to put them in the trial and, importantly, make them available to patients. (istock)

“The findings support the hypothesis that common dementia can be caused by the virus. Bacterial infectionand supports recent interest in vaccines, including BCG vaccines for tuberculosis and lowering the risk of dementia,” the researchers wrote in the release.

Anti-inflammatory drugs such as ibuprofen have also been found to reduce the risk of dementia.

“Inflammation is seen to contribute to an increasingly widespread disease, and its role in dementia is supported by the fact that several genes that increase the risk of dementia are part of the inflammatory pathway. “The release states.

Two Alzheimer’s drugs help patients live independently at home for longer

Some drugs were associated with an increased risk of dementia. Antipsychotics.

There was “contradictory evidence” for other classes of drugs, including those shown in blood pressure, depression and diabetes.

Senior doctor man

“Dementia has no treatment and the available drugs have challenges, but my experience highlights the value of personalized care,” says one doctor (not pictured) Fox News Digital. I spoke to. (istock)

Currently, two drugs are approved Treatment of Alzheimer’s disease In the United States, lekanemab (rekenbi) and donanemab (kisunra).

Both are monoclonal antibodies administered via IV infusion. Experts say they work by reducing the accumulation of amyloid plaque in the brain, but they are only effective in people with early stage Alzheimer’s disease, and have the potential for some serious side effects.

“Don’t change your medication without first discussing it with your doctor.”

Dr. Chris Vercammen, a board-certified internal medicine physician at the University of California, San Francisco (UCSF), was not involved in the study, but shared his response to the findings.

“This review identifies the classes of medications associated with increased risk of dementia,” says Vercammen, a specialist in the company. Geriatric Medicine and Palliative Caretold Fox News Digital.

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“Systematic reviews offer the advantages of aggregating data across multiple studies, which can provide a more comprehensive understanding of the current state of knowledge about the subject.”

The study had several limitations, and the researchers acknowledged due to differences in how individual studies were conducted and data were collected.

Prescriptions for the elderly

One doctor said the findings are “plausible” and highlights the importance of a comprehensive drug review for older people at risk for dementia. (istock)

Vercammen agreed that reviews of these types are limited by overall quality Available research.

“In addition, unlike meta-analyses, it does not provide a summary effect size for each drug, making it difficult to accurately discuss risks.”

Despite the restrictions, Vercammen said the findings were “plausible” and highlighted the importance of a comprehensive drug review for older people at risk for dementia.

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Lourida emphasized that all drugs have benefits and risks.

“You should never change your medicine without discussing it first With your doctorand if you have concerns, you should tell them. ”

Memory Care

Personalized care includes “addressing the practical needs of those who live with dementia and their caregivers, the “second patient” who provide essential daily support.” (istock)

Vercammen agrees that patients considering new medications or treatments should consult with their physician.

“There is no cure for dementia and the available drugs present challenges, but my experience highlights the value of Personalized care“He told Fox News Digital.

Visit us for more health articles www.foxnews.com/health

“This includes addressing the practical needs of dementia and its caregivers, the “second patient,” whom it provides daily support. This is the essence of continuous and caring care without treatment. ”

Melissa Rudy is a senior health editor at Fox News Digital and a member of the Lifestyle team. Story tips can be sent to [email protected].

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