Two common Allergy medication It can cause serious reactions to some people who have stopped using it.
The US Food and Drug Administration (FDA) has issued an alert related to cetirizine (Zyrtec) or levocetirizine (Xyzal) and warns that patients who stop taking it after long-term use may experience “rare but severe itching,” a condition known as Pruritus.
Itching was reported by people I used the medicine I stopped using them every day, months or years, and then for a few more.
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In total, 209 cases (197 in the US) were reported worldwide from April 25, 2017 to July 6, 2023.
“This number only includes reports submitted to the FDA, so there may be additional cases,” the agency said in the release.
The FDA warned that two common allergic drugs could cause severe reactions in some people who stop it. (istock)
“The cases reported were rare, but sometimes serious, and patients have experienced severe itching, which is prevalent. Medical intervention. ”
Many reports described “an important and lasting impact on quality of life and ability to function,” the FDA noted.
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In most cases (90%), restarting the medication resolved the severe itching. Some (38%) gradually tapered after rebooting and succeeded.
This drug is available in both prescription and over-the-counter versions.
“This is likely due to accelerated histamine release when the blocker stops.”
The FDA said it would update its prescription information for drugs to include warnings about the risk of itching, and also ask manufacturers to add information to the Drug Facts label for the commercial version.
Cetiridine and levocetirizine are antihistamines approved for treatment Seasonal allergies According to the FDA, it is for adults and children aged 2 and older.
Patients who stop taking drugs after long-term use may experience “rare but severe itching,” a condition known as Pruritus. (istock)
The drug is also approved as an annual allergy and chronic nest treatment for patients over six months.
Those who experience severe itching after cessation of these medications Doctor; Medical professionalthe FDA advised.
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“Individuals planning long-term use of cetirizine or levocetirizine, especially for several months or more, should discuss benefits and risks with healthcare professionals who can provide advice based on your personal needs,” the agency said.
Other common side effects of cetirizine and levocetirizine include fatigue, drowsiness, cough, dry mouth, fever, sore throat, nosebleeds, and Diarrhea and vomitingwith the FDA.
According to the FDA, cetirizine and levocetirizine are antihistamines approved to treat seasonal allergies in adults and children. (istock)
Dr. Marc Siegel, a senior medical analyst and professor of clinical medicine at NYU Langone Health and Fox News, noted that these drugs are “very effective” in alleviating allergic symptoms.
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“The FDA is paying attention to how they can be stopped in very rare circumstances after long term use. Severe itchingand will be alleviated after we resume them,” he repeated to Fox News Digital.
“This is likely due to accelerated histamine release when the blocker stops.”
“Individuals planning long-term use of cetirizine or levocetirizine, especially for several months or more, should discuss benefits and risks with healthcare professionals who can provide advice based on your personal needs,” the FDA says. (istock)
A spokesman for the Consumer Healthcare Products Association provided the following statement to Fox News Digital:
“Consumer safety is a top priority for CHPA and manufacturer members. The OTC industry supports the FDA’s ongoing commitment to making it public. Safety Signaleven in very rare cases, as in this case. ”
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“CHPA members will continue to adhere to FDA guidelines, including necessary updates to drug fact labels, whilst assessing and monitoring the latest science and product profiles. Consumers who use these drugs daily for a long period (a few months) should not stop taking their medication suddenly without first consulting with their healthcare provider.”
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Opella, the maker of Xyzal, shared the following statement with Fox News Digital:
“Xyzal has a strong track record of safety and efficacy. Scientific research and user satisfaction. This is a rare reaction, and Opella represents the safety of Xyzal when used according to the instructions. ”
