Contraceptives desogestrel Linked to a slight increase in development risk Intracranial meningioma Brain tumors in new research – risk is relatively low and only manifested in long-term use of desegestrel.
These tumors are usually non-cancerous, but can lead to neurological problems and sometimes require surgery. It is found in meningiomas It was previously linked To synthetic progestogen drugs like desegestrel designed to mimic natural hormones Progesterone It is important in the menstrual cycle and pregnancy.
Researchers led by the French National Medical and Health Product Safety team wanted to build on these previous studies to check the risk of desegestrel.
The study estimated that one in 17,331 women who have been using desogenstrel continuously for more than five years will develop a tumor that requires surgery. Within 5 years, the risk is 1 67,300.
It is relatively small and means that the way research is structured does not show direct causes and effects. However, the research team recommends caution by extending this Contraceptivesand regular tests of brain problems.
“Monitoroma monitoring should focus on women who have used desogenstrel 75 micrograms for over five years. write Researcher of published papers.
“Like other progestogens, risk increased with duration of use and after use of progestogens of known and related related risks.”
The survey results are based on records of 92,301 women, with an average age of 59.7 years. Each of the 8,391 women in that group who underwent surgery for meningioma was compared to 10 tumor-free women, tailored to age and location.
In addition to focusing on small increases in risk, researchers also observed that the association disappeared after a year without taking desogestrel. That’s good news and might help Future treatment.
“While direct evidence is still lacking, meningioma regression is expected along with the arrest of other progestogen-induced meningiomas, it may be possible that treatment will be stopped if deosteo-associated meningioma is diagnosed.” Jill Reuter, a neurosurgeon from the Center at Hospiaria University Delige, Belgium, who was not involved in the study. I’m writing In the accompanying editorial.
The same analysis also examined the researchers. Levonorgestrelanother synthetic progestogen, in this case the data did not increase risk even after 5 years of use.
In other words, taking levonorgestrel may be a better option for older women than some of the other contraceptives It was previously linked For the risk of meningioma – As always, it is important to consult with a healthcare professional to make drug and treatment decisions.
“Generally speaking, we believe that this study should not cause an alarm, but it does not only encourage discussions about the best female birth control options by women.” say Gino Pecolaro, an obstetrician and gynecologist from the University of Queensland in Australia, was not involved in the study.
This study is published in BMJ.
