Previous studies have shown that vitamin D deficiency can increase the risk of Multiple Sclerosis (MS) – And new research suggests that high dose supplementation may help relieve symptoms.
This study included 303 French adults who had experienced clinically isolated syndrome (CIS). Neurological symptoms It could lead to MS within the last 90 days.
One group of participants took a high dose of cholecalciferol (vitamin D3) (100,000 IU) for 24 months every two weeks.
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Among the group, 60.3% experienced recurrence of symptoms or new or expanded lesions on MRI scans.
One group of participants took a high dose of cholecalciferol (vitamin D3) (100,000 IU) for 24 months every two weeks. (istock)
In comparison, 74.1% of people who took the placebo experienced these same effects. This is a “statistically significant difference,” written by researchers from the French Centre for Multiple Sclerosis, Tunimus, University of Montpellier.
The results of the double-blind, randomized study were published in the journal JAMA.
“Oral cholecalciferol 100 significantly reduced disease activity in CIS and early relapse-ruption MS every two weeks,” the researchers wrote.
“These results ensure further investigation, including the potential role of pulsed high dose vitamin D as an add-on therapy.”
Of patients taking vitamin D supplements, 60.3% experienced recurrence of symptoms or new or enlarged lesions on MRI scans. (istock)
Bruce Bebo, vice president of research at the National MS Association of Oregon, was not involved in the research, but commented on what he explained to Fox News Digital.Well-designed research. ”
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“These findings suggest that high doses of vitamin D may be a promising approach to reducing disease activity in a very high level. Early Stages of MSHe said.
However, in a previously published study, Vivo used low doses, but according to Bebo, it was unable to link vitamin D supplementation with reduced MS disease activity.
“Oral cholecalciferol 100 significantly reduced disease activity in CIS and early relapse-ruption MS every two weeks,” the researchers wrote. (istock)
“Overall, the evidence suggests that the effects of vitamin D supplementation are modest, require high doses and are most effective when taken during the course of the disease by people who are deficient in vitamin D,” he said.
The American Neurological Association currently recommends a range of 300 to 4,000 units per day for adults. Health AuthorityBebo pointed out.
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“It is important to note that JAMA studies use significant doses (100,000 units per day). Although they have not reported any adverse events, excessive vitamin D intake can be toxic,” he warned.
“High doses can cause excess calcium in the blood Nausea, vomitingweakness, frequent urination, and in some cases kidney damage.
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Anyone with MS who is interested in supplementing vitamin D should talk to a neurologist Primary Healthcare Provider To determine the best approach, he recommended.
