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Home»Health»Scientists develop world’s first test for pancreatic cancer – using tiny WORMS that sniff out tumors

Scientists develop world’s first test for pancreatic cancer – using tiny WORMS that sniff out tumors

u1news-staffBy u1news-staffNovember 30, 2022No Comments6 Mins Read
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Scientists have developed the world’s first early screening test for pancreatic cancer using worms to sniff out tumors.

According to its makers, testing rolled out this month Japan — Cancer detection is 100% accurate and can be detected at an early stage.

Hirotsu Bioscience, a Tokyo-based biotech company, hopes to bring the test to the United States by next year.

The user mails the urine sample to the laboratory. This sample is added to a Petri dish filled with dozens of nematodes, called nematodes, about one millimeter long.

They are known for their strong sense of smell, which they use in the wild to locate their prey.

That makes a one-millimeter-long animal a powerful diagnostic tool, says Takaaki Hirotsu, the company’s founder and CEO, who has been studying animals for 28 years.

Urine samples are added to Petri dishes containing dozens of tiny nematodes genetically engineered to swim away from pancreatic cancer tracks

Pancreatic cancer survival rates decline rapidly over time from the time of initial diagnosis.  According to Cancer.net, the general five-year survival rate in the United States is 11%.

Pancreatic cancer survival rates decline rapidly over time from the time of initial diagnosis. According to Cancer.net, the general five-year survival rate in the United States is 11%.

How do tests work?

The user mails the urine sample to the laboratory. This sample is added to a Petri dish filled with dozens of nematodes, called nematodes, about one millimeter long.

They are known for their very strong sense of smell, which they use to locate prey in the wild.

Scientists have genetically engineered worms to swim away from pancreatic cancer tracks.

test research We have shown that it is more effective in detecting urinary cancer tumors than other widely used detection methods, such as using patient blood.

HirotsuBio started the first N-NOSE test in January 2020. This claimed to indicate whether a user had an increased risk of cancer.

Approximately 250,000 people were tested and 5-6% received high-risk readings.

The pancreatic test kit is sold directly to consumers, rather than being referred by a medical professional for testing, and is priced at $505.

First, we focused on pancreatic cancer, which is difficult to diagnose and progresses quickly.

Also, there is no single diagnostic test that can tell if you have pancreatic cancer.

The company plans to roll out similar tests for liver, cervical and breast cancer in the next few years.

However, some doctors are skeptical of the results and the consumer-based approach.

Hirotsu genetically engineered the worms to swim away from pancreatic cancer samples.

test research showed that it is more effective in detecting bladder cancer tumors than other widely used detection methods such as blood tests.

Pancreatic cancer is one of the deadliest types because it is difficult to detect early due to the lack of symptoms and is usually too late when it is discovered.

About 50,000 Americans die of pancreatic cancer each year, and only 1 in 10 survives five years after diagnosis.

Because it is marketed directly to patients, no FDA approval is required to make this test available in the United States.

“What is very important in the early detection of cancer and this kind of disease is the ability to detect very small amounts,” Hirotsu said.

“For that matter, I don’t think machines have a chance against the abilities that living things have.”

HirotsuBio started the first N-NOSE test in January 2020. This claimed to indicate whether a user had an increased risk of cancer.

About 250,000 people have taken the test, with 5-6% taking high-risk readings.

The pancreatic test kit is sold directly to consumers, rather than being referred by a medical professional for testing, and is priced at $505.

First, we focused on pancreatic cancer, which is difficult to diagnose and progresses quickly.

Also, there is no single diagnostic test that can tell if you have pancreatic cancer.

The company plans to roll out similar tests for liver, cervical and breast cancer in the next few years.

However, some doctors are skeptical of the results and the consumer-based approach.

Masahiro Jin, head of the think tank at the Institute of Medical Governance in Tokyo, warned that the false positives could far outnumber the actual cases of pancreatic cancer, making the results “useless.”

Hirotsu argued that the test’s accuracy is comparable to other diagnostic tools and that it is intended as an early screening method to allow patients to access further testing and treatment without delay.

Eric Di Luccio, chief technology officer at Hirotsu Bio Science, examines nematodes in petri dishes in the company's lab in Fujisawa, Japan.

Eric Di Luccio, chief technology officer at Hirotsu Bio Science, examines nematodes in petri dishes in the company’s lab in Fujisawa, Japan.

Television ads featuring caricatures of helminths and pancreases have been used to whip tests in Japan and will help build the company’s brand, Hirotsu said.

He added that if the company can scale, the high cost of testing could come down over time.

When asked if he particularly likes earthworms, Hirotsu said, “I feel like I should answer that I like nematodes and they’re cute, but that’s not the case at all.

“Really, I just think of them as research material.”

What is pancreatic cancer?

Pancreatic cancer is one of the deadliest diseases. About 95% of those infected die.

Joan Crawford, Patrick Swayze and Luciano Pavarotti died of pancreatic cancer.

This is the fourth most common gun killer in the United States. About 10,000 people in the UK and 50,000 in the US are diagnosed with pancreatic cancer each year.

what is the reason?

It is caused by the abnormal and uncontrolled growth of cells in the pancreas, a large gland in the digestive system.

Who is most at risk?

Most cases (90%) are in people over the age of 55. About half of all new cases occur in people over the age of 75. Her 1 in 10 is due to heredity.

Other causes include age, smoking and other health conditions including diabetes. About 80% of pancreatic cancer patients have some form of diabetes.

Why is it so deadly?

Pancreatic cancer is usually asymptomatic in its more manageable early stages.

Around stage 3 or 4, patients tend to start developing obvious symptoms such as jaundice and abdominal pain, which has likely already spread to other organs.

What is the survival rate?

All stages of pancreatic cancer combined have a one-year survival rate of 20%. In five years, that percentage drops to just 9%.

If the cancer is found at stage 1A, the 5-year survival rate is about 14% and 12% for stage 1B.

In Stage 2, these rates are 7% and 5% respectively. Only 3% of people with stage 3 pancreatic cancer survive an additional 5 years.

By stage IV, the 5-year survival rate drops to just 1%.

What are the treatment options?

The only effective treatment is removal of the pancreas. This has proven to be of little benefit in patients whose cancer has spread to other organs. In such cases, palliative care is recommended to relieve pain at the end of life.

cancer Daily mail develop health Japan pancreatic Scientists sniff test Tiny tumors Worlds WORMS
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