GLP-1 weight loss and Diabetic medicationsuch as Ozempic and Wegovy, have been shown to reduce symptoms of painful skin conditions.
According to Mayo Clinic, Hidradenitis Suppurativa, also known as Inversa, is a condition in which small, painful masses develop under the skin.
These masses usually occur in areas of the body where the skin can rub together and recur.
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According to Mayo Clinic, Hidradenitis flames in Suppurativa tend to begin after puberty, before age 40, lasts for many years and can potentially worsen over time. Women are three times more likely to develop the condition.
Medical and Surgery therapy It manages your condition and prevents complications.
A new study published in the journal Jama Dermatology analyzed how GLP-1 drugs affect this skin condition.
French researchers noted that supreutiva hydradene flames are usually related Overweight and obeseaffects 50% of these patients.
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Experts noted that weight loss has “beneficial effects” on most patients’ skin conditions, both diet and bariatric surgery.
As GLP-1 shows “major efficacy” With weight lossthe researchers hypothesized that drugs may also have anti-inflammatory properties that may be useful for skin symptoms.
This study evaluated 66 patients with Suppurativa Hidradenitis who were taking GLP-1 medications, followed by an average of 18.5 months.
Almost 90% of study participants had diabetes, with an average BMI of 39.4. Treatment of skin conditions was started for 53% of patients.
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Six months later, 54% of patients had reduced their symptoms.
The final consultation saw 67% of participants report a decrease, while 60% reduced the pain.
Dr. Brendan Camp, a New York dermatologist, responded to these findings with “cautious optimism.”
“It is impressive that GLP-1 receptor agonists significantly reduced the severity of HS over the median follow-up of 18.5 months. Flare and pain “He said in an interview with Fox News Digital that most of his patients were obese and had diabetes.”
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CAMP has identified how GLP-1-assisted weight loss can reduce “mechanical friction” and “fat-driven inflammation” in the sensitive area where skin conditions can occur.
GLP-1 also appears to be anti-inflammatory, which can promote skin healing and reduce the frequency of inflammatory skin disease flares, he said.
Camp noted that although the study represents a “promising treatment signal,” its retrospective design limits causal conclusions.
“There’s a great need for solid confirmation from randomized clinical trials,” he said.
Furthermore, most participants in this study were obese and diabetes. In other words, the results may not be applicable to all patients with Hidradenitis inflammation in Suppurativa.
“future Randomized trials It is necessary to determine who will benefit most and to establish safety and efficacy in the broader HS population,” Camp said.
Dermatologists currently do not recommend GLP-1 only for Suppurativa or other Hidradenitis Skin condition.
“Participants with HS should know that these findings are hopeful, but show a quality of life over several months of treatment that shows improvements in severity, frequency of flare, pain, and quality of life. GLP-1 therapy remains a treatment for HS and is not a sign of approval,” he said.
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However, those eligible for GLP-1 treatment for diabetes or obesity may find that these drugs offer “addition of potential benefits of improving HS symptoms.”
“Out-label start without clear indications should only be approached with caution under the guidance of both the dermatologist and the prescription provider,” Camp added.
